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The Campylobacter jejuni dccRS two-component system is required for optimal in vivo colonization but is dispensable for in vitro growth.

Molecular microbiology - 1 Dec 2004

MacKichan Joanna K, Gaynor Erin C, Chang Christopher, Cawthraw Shaun, Newell Diane G, Miller Jeff F, Falkow Stanley

Abstract excerpt

A Campylobacter jejuni two-component signal transduction system (TCSTS), designated dccR-dccS (diminished capacity to colonize; Cj1223c-Cj1222c), has been found to be important for in vivo colonization but dispensable for in vitro growth. A DeltadccR response regulator mutant generated using the virulent strain 81-176 background exhibited significantly reduced colonization of immunocompetent limited flora (I-LF)...

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PMID: 15554967
DOI: 10.1111/j.1365-2958.2004.04371.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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