Article
The CprS sensor kinase of the zoonotic pathogen Campylobacter jejuni influences biofilm formation and is required for optimal chick colonization.
Molecular microbiology - 1 Jan 2009
Svensson Sarah L, Davis Lindsay M, MacKichan Joanna K, Allan Brenda J, Pajaniappan Mohanasundari, Thompson Stuart A, Gaynor Erin C
Abstract excerpt
Campylobacter jejuni, a prevalent cause of bacterial gastroenteritis, must adapt to different environments to be a successful pathogen. We previously identified a C. jejuni two-component regulatory system (Cj1226/7c) as upregulated during cell infections. Analyses described herein led us to designate the system CprRS (Campylobacter planktonic growth regulation). While the response regulator was essential, a cprS...
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