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Article

A direct-sensing galactose chemoreceptor recently evolved in invasive strains of Campylobacter jejuni.

Nature communications - 20 Oct 2016

Day Christopher J, King Rebecca M, Shewell Lucy K, Tram Greg, Najnin Tahria, Hartley-Tassell Lauren E, Wilson Jennifer C, Fleetwood Aaron D, Zhulin Igor B, Korolik Victoria

Abstract excerpt

A rare chemotaxis receptor, Tlp11, has been previously identified in invasive strains of Campylobacter jejuni, the most prevalent cause of bacterial gastroenteritis worldwide. Here we use glycan and small-molecule arrays, as well as surface plasmon resonance, to show that Tlp11 specifically interacts with galactose. Tlp11 is required for the chemotactic response of C. jejuni to galactose, as shown using wild...

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Identifiers

PMID: 27762269
DOI: 10.1038/ncomms13206
PMCID: PMC5080441

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