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Article

Tumor-Associated Endothelial Cells with Cytogenetic Abnormalities

15 Nov 2004

Abstract excerpt

Tumor angiogenesis is necessary for solid tumor progression and metastasis. Tumor blood vessels have been shown to differ from normal counterparts, for example, by changes in morphology. An important concept in tumor angiogenesis is that tumor endothelial cells are assumed to be genetically normal, although these endothelial cells are structurally and functionally abnormal. However, we hypothesized that given the...

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PMID: 15548691
DOI: 10.1158/0008-5472.can-04-1567

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