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Article

Effects of adrenomedullin on endothelial cells in the multistep process of angiogenesis: involvement of CRLR/RAMP2 and CRLR/RAMP3 receptors.

International journal of cancer - 1 Mar 2004

Fernandez-Sauze Samantha, Delfino Christine, Mabrouk Kamel, Dussert Christophe, Chinot Olivier, Martin Pierre-Marie, Grisoli Francois, Ouafik L'Houcine, Boudouresque Françoise

Abstract excerpt

Recently, we demonstrated that U87 glioblastoma xenograft tumors treated with anti-adrenomedullin (AM) antibody were less vascularized than control tumors, suggesting that AM might be involved in neovascularization and/or vessel stabilization. Angiogenesis, the sprouting of new capillaries from preexisting blood vessels, is a multistep process that involves migration and proliferation of endothelial cells,...

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Source

Identifiers

PMID: 14712479
DOI: 10.1002/ijc.11663

Genes

RAMP2
RAMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Effects of adrenomedullin on endothelial cells in the multistep process of angiogenesis: involvement of CRLR/RAMP2 and CRLR/RAMP3 receptors.PMID 14712479Read ↗

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