Article
PAC1-R null isoform expression in human prostate cancer tissue.
The Prostate - 1 Apr 2006
Mammi Caterina, Frajese Giovanni V, Vespasiani Giuseppe, Mariani Stefania, Gnessi Lucio, Farini Donatella, Fabbri Andrea, Frajese Gaetano, Moretti Costanzo
Abstract excerpt
BACKGROUND: PACAP is a member of the VIP/GHRH family of neuropeptides and has important effects on prostate cell proliferation. Here we analyze the expression and localization of PACAP and its specific receptor variants (PAC(1)-R) in tissues collected from patients undergoing prostate biopsy and surgery for benign prostatic hyperplasia (BPH) and prostate cancer (PCa). METHODS: Reverse transcriptase...
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