Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Growth hormone-releasing hormone (GHRH) promotes metastatic phenotypes through EGFR/HER2 transactivation in prostate cancer cells.

Molecular and cellular endocrinology - 5 May 2017

Muñoz-Moreno Laura, Bajo Ana M, Prieto Juan C, Carmena María J

Abstract excerpt

The involvement of growth hormone-releasing hormone (GHRH) in several relevant processes that contribute to prostate cancer progression was analyzed. Firstly, we evaluated GHRH effects on cell proliferation and adhesion in human cancer prostate cell lines, LNCaP and PC3, by using specific assays (BrdU incorporation and collagen adhesion). The expression levels of the main marker molecules of these processes were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Cell Adhesion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Growth Hormone-Releasing Hormone

Share to Neoplasm Metastasis

Share to Proliferating Cell Nuclear Antigen

Share to Receptor, ErbB-2

Share to Transcriptional Activation

Share to Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 28193499
DOI: 10.1016/j.mce.2017.02.011

Genes

GHRH
EGFR
PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Growth hormone-releasing hormone (GHRH) promotes metastatic phenotypes through EGFR/HER2 transactivation in prostate cancer cells.PMID 28193499Read ↗

Blocking GRP/GRP-R Signaling Decreases Expression of Androgen Receptor Splice Variants and Inhibits Tumor Growth in Castration-resistant Prostate CancerSemantic proximity Read ↗

Risk of hormone escape in a human prostate cancer model depends on therapy modalities and can be reduced by tyrosine kinase inhibitors.Semantic proximity Read ↗

G Proteins in Cancer: The Prostate Cancer ParadigmSemantic proximity Read ↗

The neuroendocrine phenotype in prostate cancer: basic and clinical aspects.Semantic proximity Read ↗

Growth Hormone-Releasing Hormone (GHRH) Antagonist Peptides Combined with PI3K Isoform Inhibitors Enhances Cell Death in Prostate CancerSemantic proximity Read ↗

Knocking down gene expression for growth hormone-releasing hormone inhibits proliferation of human cancer cell linesSemantic proximity Read ↗

N-(4-hydroxyphenyl)retinamide (4-HPR) decreases neoplastic properties of human prostate cells: an agent for prevention.Semantic proximity Read ↗

[Therapy of hormone refractory prostate cancer: new standards, new trends].Semantic proximity Read ↗

Finasteride Inhibits Human Prostate Cancer Cell Invasion through MMP2 and MMP9 DownregulationSemantic proximity Read ↗

Gonadotropin‐releasing hormone: GnRH receptor signaling in extrapituitary tissuesSemantic proximity Read ↗

Elevated serum progastrin-releasing peptide (31-98) in metastatic and androgen-independent prostate cancer patients.Semantic proximity Read ↗

Isolation and sequencing of cDNAs for splice variants of growth hormone-releasing hormone receptors from human cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.