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Article

Vibrio cholerae strains with mutations in an atypical type I secretion system accumulate RTX toxin intracellularly.

Journal of bacteriology - 1 Dec 2004

Boardman Bethany Kay, Satchell Karla J Fullner

Abstract excerpt

This study shows that the Vibrio cholerae RTX toxin is secreted by a four-component type I secretion system (TISS) encoded by rtxB, rtxD, rtxE, and tolC. ATP-binding site mutations in both RtxB and RtxE blocked secretion, demonstrating that this atypical TISS requires two transport ATPases that may function as a heterodimer.

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Source

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Identifiers

PMID: 15547287
DOI: 10.1128/JB.186.23.8137-8143.2004
PMCID: PMC529086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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