Article

Acquisition, co-option, and duplication of the <i>rtx</i> toxin system and the emergence of virulence in <i>Kingella</i>

2022-11-28

Abstract excerpt

The Kingella genus includes two pathogenic species, namely K. kingae and K. negevensis , as well as strictly commensal species. Both K. kingae and K. negevensis secrete a toxin called RtxA that is absent in the commensal species. Phylogenetic analysis demonstrates that the toxin-encoding operon rtxCrtxAtolC was acquired by a common ancestor of the pathogenic Kingella species and that a preexisting type I se...

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Literature Corpus work: 40be0fef-24a2-5c6c-956e-1c00dd8dffab
DOI: 10.1101/2022.11.28.518221

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