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Thymus and immune reconstitution after allogeneic hematopoietic stem cell transplantation in humans: never say never again

6 Jan 2012

Abstract excerpt

Assessment of the host immune status is becoming a key issue in allogeneic hematopoietic stem cell transplantation (allo-HSCT). In the long-term follow-up of these patients, severe post-transplant infections, relapse or secondary malignancies may be directly related to persistent immune defects. In allo-HSCT, T-cell differentiation of donor progenitors within the recipient thymus is required to generate naive...

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PMID: 22220718
DOI: 10.1111/j.1399-0039.2011.01820.x

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