Article
The lamin CxxM motif promotes nuclear membrane growth.
Journal of cell science - 1 Dec 2004
Prüfert Kristina, Vogel Annette, Krohne Georg
Abstract excerpt
We analyzed the influence of lamins on nuclear envelope growth in cultured Xenopus A6 cells by the overexpression of human lamin A, Xenopus and zebrafish lamins B2 and Drosophila lamins Dm0 and C as GFP fusion proteins. Lamins containing a CxxM motif in their primary sequence (lamins A, B2, Dm0) induced the formation of lobulated nuclei with multi-membrane-layered, highly folded nuclear membranes and intranuclear...
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