Article
Roles of conserved proline and glycosyltransferase motifs of EmbC in biosynthesis of lipoarabinomannan.
The Journal of biological chemistry - 18 Feb 2005
Berg Stefan, Starbuck James, Torrelles Jordi B, Vissa Varalakshmi D, Crick Dean C, Chatterjee Delphi, Brennan Patrick J
Abstract excerpt
D-Arabinans, composed of D-arabinofuranose (D-Araf), dominate the structure of mycobacterial cell walls in two settings, as part of lipoarabinomannan (LAM) and arabinogalactan, each with markedly different structures and functions. Little is known of the complexity of their biosynthesis. beta-D-Arabinofuranosyl-1-monophosphoryldecaprenol is the only known sugar donor. EmbA, EmbB, and EmbC, products of the...
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