Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The factor VII activating protease G511E (Marburg) variant and cardiovascular risk.

Thrombosis and haemostasis - 1 Nov 2004

Ireland Helen, Miller George J, Webb Karen E, Cooper Jackie A, Humphries Steve E

Abstract excerpt

A previous study had shown a strong relationship between a variant in factor VII activating protease (FSAP G511E) and advanced carotid atheroma. In-vitro, the variant has reduced fibrinolytic but normal pro-coagulant activity, which may constitute a prothrombotic state. The current study has addressed risk for coronary heart disease in a prospective study of cardiovascular disorders (Northwick Park Heart Study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Diseases
Share to Cholesterol
Share to Fibrinogen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemostasis

Share to Probability

Share to Serine Endopeptidases

Share to Triglycerides

Share to United Kingdom

Source

Identifiers

PMID: 15543324
DOI: 10.1160/TH04-05-0275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The factor VII activating protease G511E (Marburg) variant and cardiovascular risk.PMID 15543324Read ↗

Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and MortalitySemantic proximity Read ↗

The G534E-polymorphism of the gene encoding the factor VII-activating protease is a risk factor for venous thrombosis and recurrent events.Semantic proximity Read ↗

The G534E polymorphism of the gene encoding the factor VII–activating protease is associated with cardiovascular risk due to increased neointima formationSemantic proximity Read ↗

Factor VII activating protease. Single nucleotide polymorphisms light the way.Semantic proximity Read ↗

Factor VII-activating protease (FSAP): vascular functions and role in atherosclerosis.Semantic proximity Read ↗

Atherothrombotic disease and factor XIII: lucky for some?Semantic proximity Read ↗

First study of C2491T FV mutation with ischaemic stroke risk in Morocco.Semantic proximity Read ↗

FXIII-A Leu34 genetic variant in premature coronary artery disease: a genotype--phenotype case control study.Semantic proximity Read ↗

Association between the Thr325Ile polymorphism of the thrombin-activatable fibrinolysis inhibitor and stroke in the Ludwigshafen Risk and Cardiovascular Health Study.Semantic proximity Read ↗

The Northwick Park Heart Study: evidence from the laboratory.Semantic proximity Read ↗

Expression of the Marburg I Single Nucleotide Polymorphism (MI-SNP) and the Marburg II Single Nucleotide Polymorphism (MII-SNP) of the Factor VII-Activating Protease (FSAP) Gene and Risk of Coronary Artery Disease (CAD): A Pilot Study in a Single Population.Semantic proximity Read ↗

The frequent Marburg I polymorphism impairs the pro-urokinase activating potency of the factor VII activating protease (FSAP).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.