Article
Transcription factor binding and induced transcription alter chromosomal c-myc replicator activity.
Molecular and cellular biology - 1 Dec 2004
Ghosh M, Liu G, Randall G, Bevington J, Leffak M
Abstract excerpt
The observation that transcriptionally active genes generally replicate early in S phase and observations of the interaction between transcription factors and replication proteins support the thesis that promoter elements may have a role in DNA replication. To test the relationship between transcription and replication we constructed HeLa cell lines in which inducible green fluorescent protein (GFP)-encoding...
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