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Article

The Enigmatic X Gene of Hepatitis B Virus

12 Nov 2004

Abstract excerpt

The exact function of HBx during HBV replication and its influence in HBV-associated hepatocellular carcinoma are still undefined, but common themes are emerging. Most studies agree that, if not absolutely essential for HBV infections, HBx at the very least plays a critical role in viral replication. HBx functions in the cytoplasm to activate various signaling pathways, many of which are controlled by modulation...

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PMID: 15542625
DOI: 10.1128/jvi.78.23.12725-12734.2004

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