Article
Interleukine-17-induced inhibitory effect on late stage murine erythroid bone marrow progenitors.
European cytokine network - 1 Jan 2000
Bugarski Diana, Krstić Aleksandra, Vlaski Marija, Petakov Marijana, Jovcić Gordana, Stojanović Nevenka, Milenković Pavel
Abstract excerpt
Recent studies have shown that the T cell-derived cytokine, interleukin-17 (IL-17), stimulates hematopoiesis, specifically granulopoiesis inducing expansion of committed and immature progenitors in bone marrow. Our previous results pointed to its role in erythropoiesis too, demonstrating significant stimulation of BFU-E and suppression of CFU-E growth in the bone marrow from normal mice. As different...
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