Article
Par-1 regulates bicoid mRNA localisation by phosphorylating Exuperantia.
Development (Cambridge, England) - 1 Dec 2004
Riechmann Veit, Ephrussi Anne
Abstract excerpt
The Ser/Thr kinase Par-1 is required for cell polarisation in diverse organisms such as yeast, worms, flies and mammals. During Drosophila oogenesis, Par-1 is required for several polarisation events, including localisation of the anterior determinant bicoid. To elucidate the molecular pathways triggered by Par-1, we have performed a genome-wide, high-throughput screen for Par-1 targets. Among the targets...
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