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Article

Lhx2-/- mice develop liver fibrosis.

Proceedings of the National Academy of Sciences of the United States of America - 23 Nov 2004

Wandzioch Ewa, Kolterud Asa, Jacobsson Maria, Friedman Scott L, Carlsson Leif

Abstract excerpt

Liver fibrosis is a wound-healing response to chronic injury of any type and is characterized by a progressive increase in deposition of extracellular matrix (ECM) proteins, the major source of which are activated hepatic stellate cells (HSCs). Because the LIM homeobox gene Lhx2 is expressed in H...

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PMID: 15536133
DOI: 10.1073/pnas.0404678101
PMCID: PMC526277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15536133-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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