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Article

UV exposure, genetic targets in melanocytic tumors and transgenic mouse models.

Photochemistry and photobiology - 1 Jan 2000

de Gruijl Frank R, van Kranen Henk J, van Schanke Arne

Abstract excerpt

The genetic changes and corruption of kinase activity in melanomas appear to revolve around a central axis: mitogenic signaling along the RAS pathway down to transcription regulation by pRB. Epidemiological studies point to the importance of ultraviolet (UV) radiation in the etiology of melanoma,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15535734
DOI: 10.1562/2004-09-26-IR-328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15535734-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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