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Article

UVA, Pheomelanin and the Carcinogenesis of Melanoma

1 Jun 2000

Abstract excerpt

Cloudman S91 mouse melanoma cells vary in constitutive and inducible melanin levels. Survival, mutation induction and DNA damage were quantitated after exposure to UVB, UVA and FS20 lamps. Assuming that the observed differences are related to melanin, induced pigment is photo-protective for survival and mutation after UVB and FS20 exposure, and is photosensitizing for survival after UVA exposure. No changes in...

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PMID: 11041372
DOI: 10.1034/j.1600-0749.13.s8.25.x

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