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Article

The SOD2 Val/Val genotype enhances the risk of nonsmall cell lung carcinoma by p53 and XRCC1 polymorphisms.

Cancer - 15 Dec 2004

Liu Geoffrey, Zhou Wei, Park Sohee, Wang Lisa I, Miller David P, Wain John C, Lynch Thomas J, Su Li, Christiani David C

Abstract excerpt

BACKGROUND: Exogenous reactive oxygen species (ROS) induces DNA damage. Manganese superoxide dismutase (SOD2) catalyzes the dismutation of superoxide radicals, a major type of ROS, into hydrogen peroxide. p53 is a tumor suppressor gene, and X-ray cross-complementing group 1 (XRCC1) is involved in...

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Source

Identifiers

PMID: 15534883
DOI: 10.1002/cncr.20716

Genes

SOD2
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15534883-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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