Article
PTCH polymorphism is associated with the rate of increase in basal cell carcinoma numbers during follow-up: preliminary data on the influence of an exon 12-exon 23 haplotype.
Environmental and molecular mutagenesis - 1 Jan 2004
Strange Richard C, El-Genidy Noha, Ramachandran Sudarshan, Lovatt Tracy J, Fryer Anthony A, Smith Andrew G, Lear John T, Ichii-Jones Fumiyo, Jones Peter W, Hoban Paul R
Abstract excerpt
After first presentation with a basal cell carcinoma (BCC), patients demonstrate interindividual diversity in the rate of development of further BCCs (number/year of follow-up). The mechanism for this variation is unknown. In this study, we evaluated whether PTCH variants mediate this phenomenon....
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