Article
Hemorrhage is uncommon in new Alzheimer family with Flemish amyloid precursor protein mutation.
Neurology - 9 Nov 2004
Brooks W S, Kwok J B J, Halliday G M, Godbolt A K, Rossor M N, Creasey H, Jones A O, Schofield P R
Abstract excerpt
BACKGROUND: Most mutations in the amyloid precursor protein (APP) gene have been associated with familial Alzheimer disease (AD); however, some mutations within the Abeta-coding sequence have been described in families with recurrent cerebral hemorrhage. The APPAla692Gly (Flemish) mutation was reported in a family in which affected members developed hemorrhagic stroke, progressive dementia, or both. OBJECTIVE: To...
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