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Article

Uch2/Uch37 is the major deubiquitinating enzyme associated with the 26S proteasome in fission yeast.

Journal of molecular biology - 26 Nov 2004

Stone Miranda, Hartmann-Petersen Rasmus, Seeger Michael, Bech-Otschir Dawadschargal, Wallace Mairi, Gordon Colin

Abstract excerpt

Conjugation of proteins to ubiquitin plays a central role for a number of cellular processes including endocytosis, DNA repair and degradation by the 26S proteasome. However, ubiquitination is reversible as a number of deubiquitinating enzymes mediate the disassembly of ubiquitin-protein conjugates. Some deubiquitinating enzymes are associated with the 26S proteasome contributing to and regulating the particle's...

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PMID: 15533439
DOI: 10.1016/j.jmb.2004.09.057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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