Article

Deubiquitination of phosphoribosyl-ubiquitin conjugates by PDE domain-containing <i>Legionella</i> effectors

2019-08-23

Abstract excerpt

<h4>Summary</h4> Posttranslational protein modification by ubiquitin (Ub) is a central eukaryotic mechanism that regulates a plethora of physiological processes. Recent studies unveiled an unconventional type of ubiquitination mediated by the SidE family of Legionella pneumophila effectors, such as SdeA, that catalyzes the conjugation of Ub to a serine residue of target proteins via a phosphoribosyl linker (henc...

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Literature Corpus work: 398d4516-ccde-5c63-841d-38a84d7ff865
DOI: 10.1101/745331

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