Article
Cdc48-Ufd1-Npl4: stuck in the middle with Ub.
Current biology : CB - 14 May 2002
Bays Nathan W, Hampton Randolph Y
Abstract excerpt
The ubiquitin-proteasome pathway has a well-defined beginning and end. Target proteins are initially recognized by upstream components and tagged with polyubiquitin chains. The 26S proteasome then degrades these polyubiquitinated proteins. Until recently, it was not known what, if any, steps occurred between the initial polyubiquitination of target proteins and their final degradation. Several new papers...
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