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Article

Strong association of insulin gene INS-VNTR polymorphisms with type 1 diabetes in the Romanian population.

Romanian journal of internal medicine = Revue roumaine de medecine interne - 1 Jan 2004

Guja C, Guja Loreta, Nutland Sarah, Rance Helen, Todd J A, Ionescu-Tîrgovişte C

Abstract excerpt

Type 1 diabetes (T1DM) is a common, chronic disease with autoimmune pathogeny, conditioned by genetic factors. Class II HLA DR and DQ and insulin gene polymorphisms encode for most of the T1DM genetic susceptibility. We have previously shown that class I alleles of the insulin gene INS-VNTR locus are strongly associated with T1DM in the Romanian population. The aim of our study was to confirm the contribution of...

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Identifiers

PMID: 15529622

Genes

INS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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