Article
The study of CTLA-4 and vitamin D receptor polymorphisms in the Romanian type 1 diabetes population.
Journal of cellular and molecular medicine - 1 Jan 2000
Guja C, Marshall S, Welsh K, Merriman M, Smith A, Todd J A, Ionescu-Tîrgoviste C
Abstract excerpt
Several studies suggested that part of the genetic susceptibility for Type 1 diabetes (T1DM) is encoded by some polymorphisms of CTLA-4 gene (2q33) and of Vitamin D Receptor gene (VDR; 12q12-14). Our aim was to assess their contribution to T1DM genetic susceptibility in the Romanian population. We typed CTLA-4 49 A/G and VDR FokI (F/f), ApaI (A/a) and TaqI (T/t) polymorphisms by Sequence Specific Primer PCR...
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