Article
[Association of insulin gene variants with type 1 diabetes mellitus in Czech population].
Casopis lekaru ceskych - 1 Jan 2004
Cinek O, Drevínek P, Sumník Z, Bendlová B, Vavrinec J
Abstract excerpt
BACKGROUND: The objective of the study was to quantify the association of insulin gene variants with type 1 diabetes mellitus (TIDM) in the Czech population. METHODS AND RESULTS: In an association study, we compared genotypes of 332 T1DM patients (age at T1DM onset was 8.1 +/- 4.4 yrs) with 292 healthy nondiabetic controls of similar age. All subjects were previously genotyped for HLA-DQB1, -DQA1 polymorphisms...
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