Article
Polymorphisms of the fimbria fim3 gene of Bordetella pertussis strains isolated in Canada.
Journal of clinical microbiology - 1 Nov 2004
Tsang Raymond S W, Lau Allan K H, Sill Michelle L, Halperin Scott A, Van Caeseele Paul, Jamieson Frances, Martin Irene E
Abstract excerpt
The fim genes which code for the fimbria protective antigens present in both the inactivated whole-cell and acellular vaccines were analyzed in 86 Canadian Bordetella pertussis isolates. At least one of the novel mutations identified was found to involve a surface epitope that has been mapped by serum antibodies from infected or vaccinated subjects.
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