Article
Multilocus sequence typing of Bordetella pertussis based on surface protein genes.
Journal of clinical microbiology - 1 Jun 2002
van Loo Inge H M, Heuvelman Kees J, King Audrey J, Mooi Frits R
Abstract excerpt
Despite more than 50 years of vaccination, Bordetella pertussis has remained endemic in The Netherlands, causing epidemic outbreaks every 3 to 5 years. Strain variation may play a role in the persistence of B. pertussis and was studied by sequencing 15 genes coding for surface proteins, including genes for all five components of acellular pertussis vaccines: pertussis toxin (Ptx), pertactin (Prn), filamentous...
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