Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Helminth infection protects mice from anaphylaxis via IL-10-producing B cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2004

Mangan Niamh E, Fallon Rosemary E, Smith Philip, van Rooijen Nico, McKenzie Andrew N, Fallon Padraic G

Abstract excerpt

Modulation of the immune system by infection with helminth parasites, including schistosomes, is proposed to reduce the levels of allergic responses in infected individuals. In this study we investigated whether experimental infection with Schistosoma mansoni could alter the susceptibility of mice to an extreme allergic response, anaphylaxis. We formally demonstrate that S. mansoni infection protects mice from an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adoptive Transfer
Share to Anaphylaxis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to B-Lymphocyte Subsets

Share to Immunization, Passive

Share to Macrophage-1 Antigen

Share to Receptors, Interleukin-2

Share to Schistosomiasis mansoni

Share to Th2 Cells

Source

Identifiers

PMID: 15528374
DOI: 10.4049/jimmunol.173.10.6346

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Helminth infection protects mice from anaphylaxis via IL-10-producing B cells.PMID 15528374Read ↗

The role of parasites in genetic susceptibility to allergy: IgE, helminthic infection and allergy, and the evolution of the human immune system.Semantic proximity Read ↗

Role of basophils in protective immunity to parasitic infections.Semantic proximity Read ↗

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus.Semantic proximity Read ↗

CD4+ Th2 response induced by Schistosoma mansoni eggs develops rapidly, through an early, transient, Th0-like stage.Semantic proximity Read ↗

T-cell regulation in helminth parasite infections: implications for inflammatory diseases.Semantic proximity Read ↗

IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo.Semantic proximity Read ↗

The beneficial helminth parasite?Semantic proximity Read ↗

Immune modulation and modulators in Heligmosomoides polygyrus infection.Semantic proximity Read ↗

B cells induced by Schistosoma japonicum infection display diverse regulatory phenotypes and modulate CD4+ T cell response.Semantic proximity Read ↗

IL-4-secreting secondary T follicular helper (Tfh) cells arise from memory T cells, not persisting Tfh cells, through a B cell-dependent mechanism.Semantic proximity Read ↗

Myeloid Cell Phenotypes in Susceptibility and Resistance to Helminth Parasite Infections.Semantic proximity Read ↗

Functional Analysis of Effector and Regulatory T Cells in a Parasitic Nematode InfectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.