Article
Gluthatione-S-transferase P1 polymorphism I105V in familial and sporadic prostate cancer.
Cancer genetics and cytogenetics - 1 Nov 2004
Debes Jose D, Yokomizo Akira, McDonnell Shannon K, Hebbring Scott J, Christensen Gerald B, Cunningham Julie M, Jacobsen Steven J, Tindall Donald J, Liu Wanguo, Schaid Daniel J, Thibodeau Stephen N
Abstract excerpt
Several reports suggest that the glutathione-S-transferase (GST) family of enzymes is involved in a variety of cancers, due to their carcinogen-detoxification properties. A polymorphism in codon 105 of the pi variant (GSTP1 I105V), which affects the enzymatic activity of the enzyme, has been link...
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