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Methylation profile of the promoter CpG islands of 14 “drug-resistance” genes in hepatocellular carcinoma

1 Jan 2004

Abstract excerpt

AIM: To establish the DNA methylation patterns of the promoter CpG islands of 14 "drug-resistance" genes in hepatocellular carcinoma (HCC). METHODS: The methylation specific polymerase chain reaction in conjunction with sequencing verification was used to establish the methylation patterns of the 14 genes in the liver tissues of four healthy liver donors, as well as tumor and the paired non-cancerous tissues of...

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PMID: 15526362
DOI: 10.3748/wjg.v10.i23.3433

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