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Article

Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis.

The American journal of pathology - 1 Oct 2003

Lee Sun, Lee Hyeon Joo, Kim Jae-Hoon, Lee Hyo-Suk, Jang Ja June, Kang Gyeong Hoon

Abstract excerpt

To determine the methylation profile of multiple tumor-related genes during multistep hepatocarcinogenesis, we investigated the methylation status of CpG islands of 9 genes, using methylation-specific polymerase chain reaction for 60 paired hepatocellular carcinoma (HCC) and non-HCC liver tissue...

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Identifiers

PMID: 14507645
DOI: 10.1016/S0002-9440(10)63495-5
PMCID: PMC1868296

Genes

GSTP1
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14507645-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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