Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resistance to collagen-induced arthritis in a nonhuman primate species maps to the major histocompatibility complex class I region.

The Journal of experimental medicine - 1 Apr 1992

Bakker N P, van Erck M G, Otting N, Lardy N M, Noort R C, 't Hart B A, Jonker M, Bontrop R E

Abstract excerpt

Type II collagen-induced arthritis (CIA) is an experimentally inducible autoimmune disorder that is, just like several forms of human arthritis, influenced by a genetic background. Immunization of young rhesus monkeys (Macaca mulatta) with type II collagen (CII) induced CIA in about 70% of the animals. One major histocompatibility complex (MHC) class I allele was present only in young animals resistant to CIA and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Autoimmune Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to Collagen

Share to Genes, MHC Class I

Share to Macaca mulatta

Share to Major Histocompatibility Complex

Share to T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 1552289
DOI: 10.1084/jem.175.4.933
PMCID: PMC2119185

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance to collagen-induced arthritis in a nonhuman primate species maps to the major histocompatibility complex class I region.PMID 1552289Read ↗

Identification of a new non-major histocompatibility complex genetic locus on chromosome 2 that controls disease severity in collagen-induced arthritis in rats.Semantic proximity Read ↗

Identification of an Mhc-DPB1 allele involved in susceptibility to experimental autoimmune encephalomyelitis in rhesus macaques.Semantic proximity Read ↗

Modeling human arthritic diseases in nonhuman primates.Semantic proximity Read ↗

HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis.Semantic proximity Read ↗

Collagen-induced arthritis in C57BL/6 (H-2b) mice: new insights into an important disease model of rheumatoid arthritisSemantic proximity Read ↗

Collagen-Induced Arthritis as a Model of Rheumatoid ArthritisSemantic proximity Read ↗

Breaking T cell tolerance against self type II collagen in HLA-DR4-transgenic mice and development of autoimmune arthritis.Semantic proximity Read ↗

MHC-DRB alleles with amino acids Val11, Phe13, and the shared epitopes promote collagen-induced arthritis and a rapid IgG1 response in Filipino cynomolgus macaques.Semantic proximity Read ↗

Evidence of genetic susceptibility to Chlamydia trachomatis-induced pelvic inflammatory disease in the pig-tailed macaque.Semantic proximity Read ↗

A high incidence of Shigella-induced arthritis in a primate species: major histocompatibility complex class I molecules associated with resistance and susceptibility, and their relationship to HLA-B27.Semantic proximity Read ↗

Genetic control of tolerance to type II collagen and development of arthritis in an autologous collagen-induced arthritis model.Semantic proximity Read ↗

Intrinsic tolerance in autologous collagen-induced arthritis is generated by CD152-dependent CD4+ suppressor cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.