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Article

Collagen-Induced Arthritis as a Model of Rheumatoid Arthritis

1 Oct 1994

Abstract excerpt

Collagen-induced arthritis (CIA) is an animal model for the human autoimmune disease rheumatoid arthritis (RA). CIA can be induced in several species including primates by immunization with heterologous type-II collagen (CII). Polyclonal antibodies are formed upon immunization with CII that exhibit a broad range of epitope specificities (some that cross-react with hose CII); however, only antibodies directed...

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Identifiers

PMID: 7923907
DOI: 10.1006/clin.1994.1164

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