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Article

Stat6(null phenotype) human lymphocytes exhibit increased apoptosis.

The Journal of surgical research - 1 Nov 2004

Galka Eva, Thompson Jennifer Lynn, Zhang Wen Jie, Poritz Lisa S, Koltun Walter A

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (IBD) is associated with altered apoptosis and increased levels of Th1 cytokines (IL-12, TNF-alpha, and IFN-gamma). These proinflammatory events may result from dysfunctional IL-4/Stat6 signal transduction that normally promotes Th2 lymphocyte differentiatio...

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Source

Identifiers

PMID: 15522309
DOI: 10.1016/j.jss.2004.05.004

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15522309-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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