Article
Do DNA sequence variants in ABCA1 contribute to HDL cholesterol levels in the general population?
The Journal of clinical investigation - 1 Nov 2004
Pajukanta Päivi
Abstract excerpt
HDL has a key role in reverse cholesterol transport, mobilizing cholesterol from the peripheral tissues to liver. In this process, the ABC transporter A1 (ABCA1) protein controls the efflux of intracellular cholesterol to apoAI, the major apolipoprotein of HDL. Since ABCA1 mutations were discover...
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