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Article

Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis.

Chembiochem : a European journal of chemical biology - 5 Nov 2004

Luzhetskyy Andriy, Liu Tao, Fedoryshyn Marta, Ostash Bohdan, Fedorenko Viktor, Rohr Jürgen, Bechthold Andreas

Abstract excerpt

The glycosyltransferase gene lanGT3, involved in the biosynthesis of the angucyclic antibiotic landomycin A, has been characterised by targeted gene deletion. A lanGT3 mutant was shown to produce landomycin E, which consists of a trisaccharide side chain attached to the polyketide moiety. Expression of lanGT3 in the mutant restored landomycin A production. Our results indicate that LanGT3 is responsible for the...

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Identifiers

PMID: 15515090
DOI: 10.1002/cbic.200400123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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