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Article

The Ras/PKA signaling pathway of Saccharomyces cerevisiae exhibits a functional interaction with the Sin4p complex of the RNA polymerase II holoenzyme.

Genetics - 1 Sept 2001

Howard S C, Chang Y W, Budovskaya Y V, Herman P K

Abstract excerpt

Saccharomyces cerevisiae cells enter into the G(0)-like resting state, stationary phase, in response to specific types of nutrient limitation. We have initiated a genetic analysis of this resting state and have identified a collection of rye mutants that exhibit a defective transcriptional response to nutrient deprivation. These transcriptional defects appear to disrupt the control of normal growth because the...

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PMID: 11560888
DOI: 10.1093/genetics/159.1.77
PMCID: PMC1461800

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