Article
Porcine reproductive and respiratory syndrome virus field isolates differ in in vitro interferon phenotypes.
Veterinary immunology and immunopathology - 8 Dec 2004
Lee Sang-Myeong, Schommer Susan K, Kleiboeker Steven B
Abstract excerpt
Type I interferons (IFN-alpha and -beta) play an important role in the innate host defense against viral infection by inducing antiviral responses. In addition to direct antiviral activities, type I IFN serves as an important link between the innate and adaptive immune response through multiple mechanisms. Therefore, the outcome of a viral infection can be affected by IFN induction and the IFN sensitivity of a...
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