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Article

Impact of genotype 1 and 2 of porcine reproductive and respiratory syndrome viruses on interferon-α responses by plasmacytoid dendritic cells.

Veterinary research - 15 May 2013

Baumann Arnaud, Mateu Enric, Murtaugh Michael P, Summerfield Artur

Abstract excerpt

Porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) infections are characterized by prolonged viremia and viral shedding consistent with incomplete immunity. Type I interferons (IFN) are essential for mounting efficient antiviral innate and adaptive immune responses, but in a recent study, North American PRRSV genotype 2 isolates did not induce, or even strongly inhibited, IFN-α in plasmacytoid...

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Identifiers

PMID: 23675981
DOI: 10.1186/1297-9716-44-33
PMCID: PMC3672080

Genes

TLR7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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