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Selecting SNPs for association studies based on population frequencies: a novel interactive tool and its application to polygenic diseases.

In silico biology - 1 Jan 2004

Möller Steffen, Koczan Dirk, Serrano-Fernandez Pablo, Zettl Uwe K, Thiesen Hans-Jürgen, Ibrahim Saleh M

Abstract excerpt

Common complex polygenic diseases as autoimmune diseases have not been completely understood on a molecular level. While many genes are known to be involved in the pathways responsible for the phenotype, explicit causes for the susceptibility of the disease remain to be elucidated. The susceptibility to disease is thought to be the result of genetic epistatic interactions between common polymorphic genes. This...

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PMID: 15506992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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