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Article

Epione application: An integrated web‑toolkit of clinical genomics and personalized medicine in systemic lupus erythematosus.

International journal of molecular medicine - 1 Jan 2022

Papageorgiou Louis, Alkenaris Haris, Zervou Maria I, Vlachakis Dimitriοs, Matalliotakis Ioannis, Spandidos Demetrios A, Bertsias George, Goulielmos George N, Eliopoulos Elias

Abstract excerpt

Genome wide association studies (GWAS) have identified autoimmune disease‑associated loci, a number of which are involved in numerous disease‑associated pathways. However, much of the underlying genetic and pathophysiological mechanisms remain to be elucidated. Systemic lupus erythematosus (SLE) is a chronic, highly heterogeneous autoimmune disease, characterized by differences in autoantibody profile, serum...

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Identifiers

PMID: 34791504
DOI: 10.3892/ijmm.2021.5063
PMCID: PMC8612305

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