Article
[Multiple sclerosis as a polygenic disease: an update].
Genetika - 1 Mar 2010
Favorova O O, Kulakova O G, Boĭko A N
Abstract excerpt
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. The observed type of heredity associated with MS is characteristic of polygenic diseases, which is produced by a joint contribution of a number of autonomously acting or interacting polymorphic genes. Recently to identify the genes responsible for genetic predisposition to MS two main approaches have been applied: (1)...
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