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Article

Gonococcal Porin IB Activates NF-κB in Human Urethral Epithelium and Increases the Expression of Host Antiapoptotic Factors

22 Oct 2004

Abstract excerpt

Infection of human urethral epithelial cells (UECs) with Neisseria gonorrhoeae increases the transcription of several host antiapoptotic genes, including bfl-1, cox-2, and c-IAP-2. In order to identify the bacterial factor(s) responsible for eliciting these changes, the transcriptional status of apoptotic machinery was monitored in UECs challenged with certain gonococcal membrane components. Initially, we...

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PMID: 15501771
DOI: 10.1128/iai.72.11.6408-6417.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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