Article
<i>Neisseria gonorrhoeae</i> infection causes DNA damage and affects the expression of p21, p27 and p53 in non-tumor epithelial cells
30 Oct 2012
Abstract excerpt
The constant shedding and renewal of epithelial cells maintain the protection of epithelial barriers. Interference with the processes of host cell-cycle regulation and barrier integrity permits the bacterial pathogen Neisseria gonorrhoeae to effectively colonize and invade epithelial cells. Here, we show that a gonococcal infection causes DNA damage in human non-tumor vaginal VK2/E6E7 cells with an increase of...
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