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Ovarian senescence in the rhesus monkey (Macaca mulatta)

22 Oct 2004

Abstract excerpt

BACKGROUND: A decline in fertility is evident in human females past their middle thirties. This 'reproductive senescence', marked by a sharp decline in pregnancy rates, may be attributed to reductions in numbers of available oocytes and their quality. Because Old World primates exhibit ovarian morphology and physiological control and timing of menstrual cycles closely resembling those of humans, the current study...

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PMID: 15498779
DOI: 10.1093/humrep/deh576

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