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Age-Specific Gene Expression Profiles of Rhesus Monkey Ovaries Detected by Microarray Analysis

1 Jan 2015

Abstract excerpt

The biological function of human ovaries declines with age. To identify the potential molecular changes in ovarian aging, we performed genome-wide gene expression analysis by microarray of ovaries from young, middle-aged, and old rhesus monkeys. Microarray data was validated by quantitative real-time PCR. Results showed that a total of 503 (60 upregulated, 443 downregulated) and 84 (downregulated) genes were...

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PMID: 26421297
DOI: 10.1155/2015/625192

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